The most common difficulties in the manufacture of LA devices are caused by the hidden complexity of the device. As the test is composed of many elements. problems can be caused by material incompatibility, flaws in the connection of the overlapping elements or imperfect material characteristics. During the development of LFIAs, most attention has been focused on finding the most suitable detection method or choosing the best antigen or antibody. Nonetheless, it is very important to pay attention to all elements of the test, including the basic components such as the backing card. adhesive strip and cover tape, in order to produce a consistent and high-quality product.
Two formats of the LFIA can be distinguish: direct and competitive. A direct test is used for larger analytes such as p24 antigen used in the human immunodeficiency virus(HIV) test, as well as analytes with multiple antigenic sites such as human chorionic gonadotropin(hCG) used in pregnancy tests. The hCG test is an example of a sandwich-based assay, where the target is immobilized between two complementary antibodies. In the direct test, the presence of the test line indicates a positive result and the control line usually contains species-specific anti-immunoglobulin antibodies, specific for the antibody in the particular conjugate. In the case of small molecules with singal antigenic determinants, which cannot bind to two antibodies simultaneously, competitive tese used. In this type of test, the analyte blocks the binding sites on the antibodies on the line, preventing their interactions with the coloured conjugate. Therefore, a positive results is indicated by the lack of singnal in the test line, while the control line should be visible independently of the test result.
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Shanghai Jiening Biotech Co., Ltd
Shanghai Jiening Biotech Co., Ltd. is a joint venture of technical experts and professional marketers in lateral flow chromatography industry founded by James Zhou over 20 years ago,out of the need for domestically produced top quality equipment for POCT manufacturing.
Eesemedtrend Biotech (Shanghai) Co., Ltd
Eesemedtrend Biotech (Shanghai) Co., Ltd., established in 2004, is a wholly-owned American company founded by Dr. Peter Chun.
Leveraging a professional team with a combined experience of 75 years and a range of cutting-edge patented technologies, the company is dedicated to the research and development of detection technologies. It offers strategic and technical services, including customized solutions, professional technical support and product design ...
Why the Alliance?
EMB and Jiening share a common vision to provide easy access to develop and commercialize lateral flow tests. Whether you are a beginner, an experienced technical professional working in this field, or a supplier of related products, we welcome all to communicate and participate in this effort.
Training Locations
Jiening Biotech regularly organizes lateral flow chromatography experiment technique and application training courses every year. These courses are conducted by experienced lateral flow process engineers with rich theoretical knowledge and practical production experience ...
Thailand（Thailand）
Shanghai
Hong Kong
Taiwan
Pakistan
Algeria
Canada
U.S.A
Brazil
Shenzhen
Beijing
Chongqing
5
6
Training Locations
Products have been sold in overseas regions.
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Easemedtrend Biotech (Shanghai) Co., Ltd
4F, Building E, 501 Jingang Road, Pudong, Shanghai 201206, China
Tel： 021-38420186/ 50790895
Website：www.easemedtrend.com
Email：customer.service@easemedtrend.com
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